Neurologists told why it is vital to monitor the oral cavity
Topics: Research
New York University has proven that people who neglect oral hygiene are more at risk of suffering from dementia, including Alzheimer's. As reported by "Lenta.RU", the pathogenic microflora of the gums is associated with a high level of beta-amyloid protein, abnormal accumulations of which are considered dangerous for neurons.
An experiment was conducted with the recruitment of 48 elderly people without obvious signs of cognitive impairment. Scientists examined the microflora of periodontal pockets (the ratio of harmful to beneficial bacteria, known as the dysbiotic index) and compared the results with data on the presence of amyloid protein and neurofibrillary accumulations in cerebrospinal fluid.
Thus, an increased dysbiotic index (the prevalence of pathogenic microbes, including Treponema, Porphyromonas, Tannerella, over healthy microflora, including Rothia, Corynebacterium) was associated with an increase in the level of beta-amyloid protein (Aβ + group). If a high concentration of dangerous proteins was found in the samples, the risk of an increased dysbiotic index increased by 4 times.
Experts believe that pathogens can penetrate the central nervous system and have a direct pathological effect on the brain. They also cause general inflammation, which eventually spreads to the brain.
